College of Medicine Archives | University of Central 性视界传媒 News Central 性视界传媒 Research, Arts, Technology, Student Life and College News, Stories and More Thu, 13 Aug 2026 18:36:55 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.2 /wp-content/blogs.dir/20/files/2019/05/cropped-logo-150x150.png College of Medicine Archives | University of Central 性视界传媒 News 32 32 性视界传媒 Scientist to Explore Precise Treatment Targeting Weak Spots in Lyme Disease Bacteria /news/ucf-scientist-to-explore-precise-treatment-targeting-weak-spots-in-lyme-disease-bacteria/ Thu, 13 Aug 2026 13:30:56 +0000 /news/?p=154614 Through her third consecutive NIH grant renewal, Mollie Jewett aims to 鈥渟tarve鈥 Borrelia burgdorferi, preventing the tick-borne bacteria from spreading in humans and causing Lyme disease.

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Triggered by a near-painless tick bite, Lyme disease causes severe pain and inflammation for more than 475,000 people in the U.S annually, according to the Centers for Disease Control.

Medicine can treat infections after people get sick, but 性视界传媒 infectious disease expert Mollie Jewett is seeking to halt Borrelia burgdorferi bacteria, which causes Lyme disease, in its tracks without relying on general antibiotics. Her goal: 鈥渟tarve鈥 the bacteria of the nutrients they need to function before they spread through the human body.

Jewett, professor and head of the Immunity and Pathogenesis Research Division at 性视界传媒鈥檚 College of Medicine, is supported by a recently renewed five-year, $2.5 million grant from the National Institutes of Health.

性视界传媒 infectious disease expert Mollie Jewett smiles while wearing a white lab coat in a research lab.
性视界传媒 infectious disease expert Mollie Jewett.

She is entering a third consecutive federally funded research cycle with $513,314 received this year. Jewett鈥檚 research builds upon more than a decade of discoveries that have narrowed the search for ways to stop B. burgdorferi from triggering Lyme disease, one of the nation鈥檚 most common vector-borne diseases. Her team includes a 性视界传媒 undergraduate who occasionally struggled to walk because of pain from Lyme disease.

The disease is spread by blacklegged ticks that become infected after biting mammals or birds carrying the bacteria. The ticks are so small, humans often don鈥檛 notice they have been bitten. Symptoms include fever, chills, headache and fatigue, which often are misdiagnosed as a virus or the flu. Even after treatment, Lyme disease patients can face complications including nervous system and heart issues, severe fatigue and arthritic pain.

The disease is most commonly found in Maine to Virginia and in the upper Midwest but is spreading as suburban growth enters wildlife areas. 性视界传媒 reports few cases of Lyme disease annually, but travelers who go to endemic areas like New England are at increased risk.

A New Approach to Battle Borrelia

性视界传媒 researchers are focused on how B. burgdorferi manages to survive and thrive as it spreads in ticks and mammals to humans.

鈥淭he bacteria need to adapt to two different environments, and so we want to know how it does that,鈥 Jewett says. 鈥淲e鈥檙e looking at what the bacteria eat and what it needs to survive. In our lab, we call Borrelia a wimpy pathogen because it can鈥檛 make a lot of the nutrients it needs on its own, and so it scavenges what it needs from wherever it is.鈥

Researchers examine a petri dish on an illuminated light box in a lab.
Mollie Jewett and her lab analyze the purification of a novel riboflavin-dependent protein important for Borrelia burgdorferi听metabolism.

The first iteration of the NIH grant allowed the scientists to screen all of the bacteria鈥檚 genes that might be important for the infection. With the second grant, Jewett targeted three genes that appeared to play a role in spreading the infection from a bite on the skin to other parts of the human body.

“One of these three genes we found is important to the ability of the bacteria to consume riboflavin. We want to target this gene and see if we can starve the bacteria.” 鈥 Mollie Jewett, 性视界传媒 infectious disease expert

Now they have focused on riboflavin, commonly known as vitamin B2, after discovering that B. burgdorferi salvages the vitamin from each host to sustain itself.

鈥淥ne of these three genes we found is important to the ability of the bacteria to consume riboflavin,鈥 Jewett says. 鈥淲e know that riboflavin is a precursor for other cellular activities that are important to the metabolism of the bacteria. Essentially, we want to target this gene and see if we can starve the bacteria.鈥

If their theory is successful, it could lead to therapies specific to B. burgdorferi that would prevent successful bacterial infection by limiting its riboflavin uptake. An advantage of such potential treatments would be that patients don鈥檛 have to take general antibiotics that can also harm the body鈥檚 good bacteria and increase risks for antibiotic-resistant bacteria.

The 性视界传媒 team is collaborating with Baylor University scientists to trace exactly how riboflavin is used by the bacteria.

Researchers examine a petri dish on an illuminated light box in a lab.
Biomedical sciences doctoral student Anna Schulz 鈥25MS (left) uses genetic approaches to characterize Borrelia burgdorferi genes important for metabolizing vitamin B2. To accomplish this, Schulz and Jewett (right) examine bacterial colonies on solid medium plates.

Students Driving Discovery

Biomedical sciences doctoral student Anna Schulz 鈥25MS played a key role in pinpointing specific ways the bacteria use riboflavin to generate energy. She served as first author on a recent publication examining these processes, and says she鈥檚 looking forward to growing as a researcher in this next phase.

鈥淎s a first author, I took more ownership over the experiments and the writing process,鈥 Schulz says. 鈥淸Jewett] was really great about letting me lead the project as a student. Borrelia is so unique, and there鈥檚 still so much we don鈥檛 know, and that鈥檚 what keeps me engaged with this research.鈥

“… I couldn鈥檛 treat it until years after I got infected. So, I truly care about finding new treatments for Lyme disease.” 鈥 Grace Easterling, 性视界传媒 biomedical sciences student

Third-year biomedical sciences undergraduate Grace Easterling says she was drawn to Jewett鈥檚 lab because she previously developed Lyme disease and suffered tremendous joint pain. She was determined to find a way to protect others.

鈥淚t was something that, because we live in 性视界传媒, wasn鈥檛 caught early because it鈥檚 not as common,鈥 Easterling says. 鈥淚 struggled for a long time to get diagnosed, and I couldn鈥檛 treat it until years after I got infected. So, I truly care about finding new treatments for Lyme disease and understanding the bacteria.鈥

 


Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under award number R01AI099094. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Mollie-Jewett Lyme disease research Mollie-Jewett_Anna-Schulz Biomedical sciences doctoral student Anna Schulz 鈥25MS uses genetic approaches to characterize Borrelia burgdorferi听genes important for metabolizing vitamin B2. To accomplish this, Schulz and Jewett examine bacterial colonies on solid medium plates.
120 Students Join 性视界传媒 to Become Physician Knights /news/120-students-join-ucf-to-become-physician-knights/ Tue, 04 Aug 2026 13:16:11 +0000 /news/?p=154542 Chosen from 5,422 applicants, the 120 new M.D. candidates received their undergraduate degrees from Yale, Vanderbilt, Notre Dame, Duke, Case Western and Emory in addition to 性视界传媒.

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Pepi Dostal was inspired to enter medicine by his grandmother, a physician who cared for her village in the Czech Republic. Often paid with eggs or meat from her patients鈥 farms, she remains the village matriarch even after retirement.

鈥淚 saw what she means to her community,鈥 says Dostal, who comes to 性视界传媒 from the University of Washington. 鈥淎nd I wanted to do the same thing for my community.鈥

Dostal was one of 120 new 性视界传媒 College of Medicine students who received their white coats Monday in a traditional celebration that welcomes them as partners in healthcare.

Chosen from 5,422 applicants, the 120 new M.D. candidates received their undergraduate degrees from Yale, Vanderbilt, Notre Dame, Duke, Case Western and Emory in addition to 性视界传媒. They include scientists, artists, musicians, athletes, global volunteers and EMTs.

A group of students wearing white coats and posing for a photo
性视界传媒’s M.D. Class of 2030 includes scientists, community volunteers, first responders, athletes and artists.

Monday was the 18th White Coat Ceremony in the history of the medical school, which celebrates its 20th anniversary this year. In his welcome, 性视界传媒 President Alexander N. Cartwright described 鈥渨hat began as a bold vision on undeveloped land in Lake Nona has grown into a thriving Academic Health Sciences Campus and a community focused on improving lives.鈥

And he credited that growth to Deborah German, vice president for health affairs and founding dean, who has announced her transition from both roles. Monday was her last White Coat Ceremony.

鈥淒r. German helped transform an ambitious vision into the college you join today,鈥 he told students, parents, faculty and staff. 鈥淏ecause of her leadership, hundreds of physicians have begun their careers here, thousands of patients have been served, and new partnerships, discoveries, and opportunities have taken shape across Lake Nona and our state. Dr. German, your remarkable legacy will always hold a special place at 性视界传媒.鈥

The Good Doctor

For every White Coat Ceremony, German has conducted the first class of medical school called 鈥淭he Good Doctor 鈥 A 性视界传媒 Tradition.鈥

Dean Deborah German conducts the first class of medical school at 性视界传媒 鈥 The Good Doctor, a 性视界传媒 Tradition.
Dean Deborah German conducts the first class of medical school at 性视界传媒 鈥 The Good Doctor, a 性视界传媒 Tradition.

She asks first-year students to imagine the person they love most in the world is seriously ill with an undiagnosed condition. What are the traits they want to see in the doctor caring for their beloved? As students name attributes, German writes each word on a blackboard that is displayed in the College of Medicine atrium for the entire year.

The class of 2030 suggested 38 traits, including听humble, trustworthy, dedicated, knowledgeable, ethical, determined, compassionate, resilient and innovative.

鈥淭his is your听contract听with your听faculty,听friends,听family, community听and听each other,鈥 German said, pointing to the board. 鈥淎lways remember, The Good Doctor lives in each of you. With the听guidance of the faculty听and听your own hard work, you will become The Good Doctor.鈥

Nelson Jones with his family, including both parents who are nurses and inspired him to go into medicine.
Nelson Jones with his family, including both parents who are nurses and inspired him to go into medicine.

Inspired to Care for Others

As a 性视界传媒 undergraduate, Nelson Jones earned the Order of Pegasus, the university鈥檚 top student honor. Today he is a physician-in-training. Both of his parents are nurses, and he described how their care of others 鈥 especially in communities of need 鈥 inspired him. So did the opportunities 性视界传媒 provides.

鈥淚鈥檓 feeling extremely grateful and excited,鈥 he said after receiving his white coat. 鈥淭his university has built me into the person I am and will continue to build me into the physician I strive to become.鈥

Vivian Silva-Dallenbach graduated from the University of South 性视界传媒 with degrees in biomedical sciences and astronomy. She chose 性视界传媒 for medical school because of the college鈥檚 new aerospace medicine program. She鈥檚 researched how space flight affects the human body.

鈥淥nce I saw that 性视界传媒 has an aerospace medicine program, I knew it was a match,鈥 she says. 鈥淚鈥檓 particularly interested in women鈥檚 health and how we can provide specialized care for female astronauts.鈥

Dev Patel, another 性视界传媒 alum, says his dreams are inspired by the College of Medicine鈥檚 founding dean. 鈥淚 would like to take a page out of German鈥檚 book. She started with almost nothing to work with and she built something amazing here. So as we have such a long road in front of us, I鈥檓 hoping to follow in her footsteps and even have a fraction of the impact she did.鈥

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性视界传媒_-Class-of-2030-White-Coat 性视界传媒's M.D. Class of 2030 incudes scientists, community volunteers, first responders, athletes and artists. 性视界传媒_Class of 2030 White Coat_Deb German Dean Deborah German conducts the first class of medical school at 性视界传媒 鈥 The Good Doctor, a 性视界传媒 Tradition. 性视界传媒_White Coat_Class of 2030_Nelson Jones Nelson Jones with his family, including both parents who are nurses and inspired him to go into medicine.
From the Clinic to the Cockpit: 性视界传媒 Opens New FAA-Designated Clinic for Pilots /news/from-the-clinic-to-the-cockpit-ucf-opens-new-faa-designated-clinic-for-pilots/ Thu, 30 Jul 2026 17:34:48 +0000 /news/?p=154402 Through specially administered exams, 性视界传媒 faculty member William 鈥淓d鈥 Powers and his team are helping pilots stay healthy and adhere to the medical standards the FAA requires for safe aircraft operation.

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Minutes from one of the world鈥檚 most visited airports, 性视界传媒 has opened a new clinic to help pilots meet Federal Aviation Administration (FAA) medical requirements to fly safely.

The new University of Central 性视界传媒 Aerospace Medicine Clinic at 性视界传媒 Health Faculty Physician Practice in Lake Nona is led by William 鈥淓d鈥 Powers, chief medical officer of 性视界传媒鈥檚 and a certified aviation medical examiner.

Pilots operating civilian aircraft must have various levels of FAA medical certification depending on the type of aircraft. Commercial pilots must pass the exam every six months or each year.

鈥淔light safety depends on healthy pilots,鈥 says Powers, who is certified to conduct the highest level of FAA exams. 鈥淭hat鈥檚 ultimately what we鈥檙e here to support.鈥

“Here at 性视界传媒, we are … connecting medicine, engineering, research and industry in ways few universities can.” 鈥 性视界传媒 President Alexander N. Cartwright

性视界传媒 President Alexander N. Cartwright says the clinic is an example of the university鈥檚 mission to educate talent, advance discovery and solve societal challenges that matter.

鈥淭he next era of flight will bring new demands on health and human performance,鈥 Cartwright says. 鈥淗ere at 性视界传媒, we are meeting those challenges by connecting medicine, engineering, research and industry in ways few universities can.鈥

What sets this clinic apart from others is its ability to more efficiently address the health needs of pilots thanks to a network of 性视界传媒 College of Medicine faculty physicians, university officials say.

The clinic marked its opening with a ceremony today.

Assessing Safety and Minimizing Risk

Medical clearance for pilots is 鈥渁ll about risk,鈥 Powers says. 鈥淭he FAA has to assess the risk of a pilot experiencing a sudden incapacitation while flying. That鈥檚 really what these exams are focused on.鈥

For that reason, the 性视界传媒 clinic will not focus on diagnosing disease, but on identifying and acting on any condition that might endanger pilot, crew and passenger safety.

In addition to a physical exam, pilots must pass hearing and vision tests, including demonstrating that they are not color blind. Airline pilots receive an electrocardiogram every year, while other pilots, like hobbyists, may receive an electrocardiogram if there is evidence of heart disease. Physicians also review medical history and discuss any health concerns that could affect flight safety.

Even manageable chronic conditions like high blood pressure can temporarily delay certification until the condition is treated, stabilized and controlled.

鈥淲hen you鈥檙e flying an airplane, you don鈥檛 have the luxury of pulling over and waiting for help like if you鈥檙e a truck driver,鈥 Powers says. 鈥淵ou must be aware at all times. If you鈥檙e responsible for an aircraft full of passengers, the FAA wants to minimize the chance of a sudden incapacitation.鈥

A Vast Network of Expertise

Complicated medical cases are referred to the FAA for further review, and pilots may need additional interventions to meet certification standards. That鈥檚 where the College of Medicine鈥檚 physician practice offers a distinct advantage, Powers says.

“We can guide pilots to the specialists and testing they need and help them get back on the path toward medical clearance.” 鈥 William “Ed” Powers, chief medical officer of the CASEEM

Unlike private clinics that do pilot certification exams, 性视界传媒 offers multiple medical specialties under one roof and a team approach to care.

鈥淲e can guide pilots to the specialists and testing they need and help them get back on the path toward medical clearance,鈥 Powers says.

Powers brings decades of expertise in space and aviation medicine. Before joining 性视界传媒, he was chief of NASA鈥檚 Medical Operations Branch, director of flight medicine for Axiom Space and director of the aerospace medicine residency program at the University of Texas Medical Branch in Galveston.

Powers also worked inside the FAA as a supervisory medical officer. He says that experience gives him a firm understanding of what the FAA requires, making the process smoother for everyone.

鈥淭hat means fewer delays, fewer mistakes in paperwork and a more efficient process for pilots whose livelihoods depend on getting certified,鈥 he says.

William 鈥淓d鈥 Powers demonstrates part of a hearing test with a standardized patient. Pilots are assessed for hearing, vision, cardiovascular health and more to ensure pilot safety and eliminate the risk of sudden incapacitation.

Strengthening the Regional Aviation Ecosystem

Another 性视界传媒 advantage: the clinic is only about 10 miles from Orlando International Airport, which welcomes 58 million travelers annually. So in addition to local aviators, pilots nationwide who travel to and through Orlando could easily schedule their certification exams at 性视界传媒.

“Clinics like 性视界传媒鈥檚 Aerospace Medicine Clinic [are] helping pilots, whether in space or on the ground, access the care and medical certification support they need to remain flight-ready.” 鈥 Lance Lyttle, CEO of the Greater Orlando Aviation Authority

The clinic will help strengthen the aviation training pipeline in one of the nation鈥檚 most active aerospace regions. This capability is especially important for local flight schools whose students may require guidance in navigating medical certification, return-to-flight concerns and the health demands of aviation careers.

鈥淐entral 性视界传媒鈥檚 aviation ecosystem is built on more than runways, terminals and launchpads,鈥 says Lance Lyttle, CEO of the Greater Orlando Aviation Authority, which manages Orlando International and Orlando Executive airports. 鈥淚t also depends on the people and services that keep aviation moving safely and efficiently. Clinics like 性视界传媒鈥檚 Aerospace Medicine Clinic complement that ecosystem by helping pilots, whether in space or on the ground, access the care and medical certification support they need to remain flight-ready.鈥

The clinic is embedded in Central 性视界传媒鈥檚 bustling travel hub with numerous satellite airports, including Kissimmee Gateway Airport and Orlando Sanford International Airport. Giving pilots another option to get cleared to fly strengthens the regional economy, says Shaun Germolus, director of aviation for the Kissimmee facility.

鈥淭he aviation industry in Central 性视界传媒 provides a major economic impact to the region,鈥 Germolus says. 鈥淭he medical exams and certificates provided by the 性视界传媒 Aerospace Medicine Clinic will be very valuable to ensure our aviation professionals are healthy and readily available to serve.鈥

Launching the Clinic

The clinic is starting with limited Thursday and Friday morning appointments to allow the team to refine operations before expanding. Helping coordinate those efforts is Camila Niebla 鈥26, a 性视界传媒 health sciences graduate who now serves as the clinic鈥檚 aerospace medicine navigator.

Niebla discovered aerospace medicine by accident while exploring future career paths before applying to medical school.

鈥淚 didn鈥檛 even know aerospace medicine was a possibility,鈥 she says. 鈥淚鈥檝e always been interested in performance-driven medicine, like sports medicine, so this felt really exciting. It鈥檚 exciting to be part of something from the beginning and watch it grow.鈥

Part of a Larger Vision for Aerospace Medicine at 性视界传媒

The clinic is part of 性视界传媒鈥檚 , which is being developed as a comprehensive academic, clinical, research, education, and operational platform to support the future of aviation, commercial spaceflight, and human space exploration.

鈥淭his is about building the medical infrastructure required for the next era of flight, both on Earth and in space,鈥 says Emmanuel Urquieta, vice chair for aerospace medicine at the 性视界传媒 College of Medicine. 鈥淥ur goal is to create a program that is not only academic, but operational and translational in nature 鈥 one that supports student pilots, flight schools, commercial aviation, spaceflight providers and the broader aerospace ecosystem.鈥

Schedule an Appointment

to learn more about FAA medical exams at 性视界传媒 Health Faculty Physician Practice and schedule an appointment online.

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FAA flight exam William 鈥淓d鈥 Powers demonstrates part of a hearing test with a standardized patient. Pilots are assessed for hearing, vision, cardiovascular health and more to ensure pilot safety and eliminate the risk of sudden incapacitation.
性视界传媒 Students, VA Doctor Develop AI Tool to Help Doctors Identify Chronic Pelvic Pain /news/ucf-students-va-doctor-develop-ai-tool-to-help-doctors-identify-chronic-pelvic-pain/ Tue, 28 Jul 2026 15:30:57 +0000 /news/?p=154477 Through a yearlong internship, two 性视界传媒 undergraduates created an AI-assisted application that helps guide healthcare providers and patients towards accurate diagnosis of the source of chronic pelvic pain.

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For millions of women living with chronic pelvic pain (CPP), finding answers can take far too long.

Studies have shown the condition affects nearly one in four women worldwide and is linked to dozens of potential disorders involving multiple organ systems. Yet many healthcare providers receive only limited training in diagnosing the source of pain, often leaving patients facing years of uncertainty, repeated testing and ineffective treatments before receiving the right diagnosis.

A yearlong collaboration between a 性视界传媒 physician-scientist and two biomedical sciences undergraduate students aims to create a better environment for doctors and patients to reach an understanding together. Biomedical sciences students Sarah Gabriela Nieto Chavarro and second-year Juliana Dimetry interned with Georgine Lamvu, a 性视界传媒 College of Medicine volunteer professor of obstetrics and gynecology, to transform years of international research into a practical tool to help clinicians evaluate patients more quickly and confidently.

The team is developing an AI-assisted clinical questionnaire application that guides physicians through a patient’s symptoms and identifies which organ systems and conditions should be examined. Rather than replacing a physician鈥檚 judgment, the application compiles patient histories quickly to help guide physicians toward making a clearer diagnosis.

From International Research to a Practical Tool

Despite the prevalence of CPP, many healthcare providers lack specialized training in diagnosing the underlying condition because symptoms often overlap with gastrointestinal, urinary, musculoskeletal and reproductive disorders.

鈥淲e鈥檙e hoping that this can become easy to use and can take a detailed medical history that could take an hour to get through down to just 5 to 10 minutes.鈥 鈥 Georgine Lamvu, volunteer professor and Orlando VA practitioner

鈥淲e鈥檙e hoping that this can become easy to use and can take a detailed medical history that could take an hour to get through down to just 5 to 10 minutes,鈥 says Lamvu, who practices at the U.S. Department of Veterans Affairs Medical Center in Orlando and directs its gynecological surgery fellowship program and center. 鈥淭hat allows physicians to have a more efficient evaluation and spend more time with the patient.鈥

The center is a pioneering program designed to address the growing demand for specialized gynecologic care among women veterans. As the number of women veterans using VA healthcare services is expected to increase significantly, this fellowship and center aims to train highly skilled gynecologists to meet their healthcare needs within the VA system and beyond.

As part of that initiative, this project builds upon nearly five years of work led by Lamvu alongside an international coalition of physicians, researchers and patient advocacy groups.

Their research culminated in an international consensus called R U MOVING SOMe, an acronym that categorizes the broad range of symptoms associated with chronic pelvic pain and is the basis of the AI-tool Lamvu and her team developed.

Finding a Definitive Diagnosis

Lamvu says the team translated the clinical research into the logic behind a chatbot-style application that asks fewer than 20 targeted questions. Physicians enter a patient鈥檚 symptoms and history into the program, which then suggests the organ systems and conditions most likely responsible for the pain, helping clinicians focus their evaluation.

The team plans to expand the application beyond patient questionnaires by incorporating physical examination findings into the same scoring system. Ultimately, the researchers say they hope it can be used in any practice that serves women, but it may be years away from being realized.

鈥淧hysicians just need a way of processing all the information that comes from the patient to narrow it down to a differential diagnosis,鈥 Lamvu says. 鈥淩ight now, it鈥檚 all too common to see healthcare workers panic a little when they hear a patient has chronic pelvic pain because it’s considered a complex condition.鈥

Four people posing for a photo
Biomedical sciences students Sarah Gabriela Nieto Chavarro (left) and Juliana Dimetry (right) with Associate Professor of Medicine Kersten Schroeder (second from right), who was instrumental in facilitating the internship with 性视界传媒 College of Medicine Volunteer Professor Georgine Lamvu (second from left) at the Orlando VA.

An Inspiring Internship

The students sifted through years of research and developed the logic for the AI in less than a year. Given the complexity of CPP and the vast amount of data, Lamvu says she is impressed by Dimetry and Nieto Chavarro.

鈥淭hey learned valuable lessons, like if you see a problem that seems unsolvable to everyone else and that directly and negatively impacts patients, you have the power to do something about it,鈥 she says. 鈥淭hese are experiences not every student gets to have, especially this early on in their life.鈥

Dimetry says she challenge intrigued her, and that she was drawn to the project for the opportunity to be at the forefront of medicine and emerging technology.

鈥淚 think that adapting the field of medicine to AI in ways such as this project is necessary to keep medicine growing and advancing,鈥 she says. 鈥淚 also saw how impactful this project could be if done successfully, and I wanted to be a part of that and make a difference,鈥

For Nieto Chavarro, who graduates Summer 2026, the experience showed her how to use technology to help deliver compassionate patient care.

鈥淥n a personal level, this experience has taught me to keep going and to never give up,鈥 Nieto Chavarro says. 鈥淎ll of this has ultimately reinforced how essential it is to genuinely listen to patients so they feel safe and understood鈥

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VA CPP research story with Dr. Lamvu (10) Biomedical sciences students Sarah Gabriela Nieto Chavarro (left), 性视界传媒 College of Medicine Volunteer Professor Georgine Lamvu (second from left) and Juliana Dimetry (right) with Associate Professor of Medicine Kersten Schroeder (second from right), who was instrumental in facilitating the internship. (Photo by Eddy Duryea '13)
性视界传媒 Engineering Students’ Excellence Celebrated With 2026 Astronaut Scholarship /news/ucf-engineering-students-excellence-celebrated-with-2026-astronaut-scholarship/ Fri, 24 Jul 2026 13:03:42 +0000 /news/?p=154412 The prestigious scholarship offers financial support up to $15,000 in addition to mentorship and extensive networking opportunities.

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Joshua Taggart knew he wanted to work for the space industry the day he experienced his first launch while attending a camp at Kennedy Space Center, seeing the space shuttle Endeavour soar into the sky. He鈥檚 now closer to making that dream a reality after being recognized with one of the industry鈥檚 most distinguished awards.

Taggart is the latest Knight to receive the coveted Astronaut Foundation Scholarship, a national award that provides more than 70 scholarships of up to $15,000 each for some of the nation鈥檚 very best STEM students. He will be recognized with the 2026 class of scholars at the foundation鈥檚 gala, to be held next month in Houston.

Taggart says he chose 性视界传媒 for its reputation in engineering as the No. 1 supplier of talent to the nation鈥檚 aerospace and defense industries (Aviation Week Network). He is in good company as part of a trio of Astronaut Scholars this year from the College of Engineering and Computer Science, joining mechanical engineering student Keanu Brayman and computer engineering student Kyle Coutray (a biomedical sciences double major), who have received the scholarship for second consecutive year.

As Taggart works to complete his final year at 性视界传媒, his latest accomplishment fuels his path to make an impact as a future space researcher.

Man with shoulder length dark hair and glasses wearing a blue NASA collar shirt stands in front of white wall with NASA logo
Joshua Taggart chose 性视界传媒 for its reputation in engineering as the No. 1 supplier of talent to the nation鈥檚 aerospace and defense industries (Aviation Week Network). (Photo courtesy of Joshua Taggart)

Future Focused

Driven to contribute to humanity鈥檚 exploration of our universe, Taggart is already working on future-focused innovations that can benefit the space industry.

Through NASA Office of STEM Engagement, he interned at the Johnson Space Center working on communications, avionics, propulsion and flight software for CubeSat subsystems.

This summer at NASA鈥檚 Glenn Research Center, he is researching packaging materials for silicon carbide pressure sensors, working to make sure they perform reliably above 1,000 degrees Celsius (1,832 degrees Fahrenheit), and on integrating thermocouple sensors for temperature compensation.

鈥淚 chose this field of research because I want to be involved in next-generation electronics that can withstand the extreme nature of outer space.鈥 鈥 Joshua Taggart

鈥淲ith the harsh environment that outer space is and planet surfaces like Venus, electronics must survive very high temperatures and radiation effects,鈥 he says. 鈥淚 chose this field of research because I want to be involved in next-generation electronics that can withstand the extreme nature of outer space.鈥

His work as an undergraduate researcher for the Q-Sim Lab, directed by Assistant Professor Jaesung Lee, also centers around developing technology designed to operate in outer space. Taggart is working on microelectromechanical systems (MEMS) resonators designed to perform under extreme conditions, such as elevated temperatures and increased exposure to radiation.

He recently won a Judge鈥檚 Choice Award at 性视界传媒 Student Research Week for his Honors Undergraduate Thesis, 鈥淩obust AlN MEMS Resonators for High Temperature Space Environments.鈥

His passion for space has only grown over the years, reflected by his ongoing research at 性视界传媒 and for NASA. As an Astronaut Scholar, Taggart is launching into a future full of possibilities.

鈥淎side from the financial support that this scholarship will provide me as I complete my undergraduate program, I am very eager for all of the networking opportunities I will have,鈥 Taggart says. 鈥淚 look forward to networking with other students and industry leaders to learn and grow as much as I can thanks to the Astronaut Scholarship Foundation.鈥

Those interested in the Astronaut Scholarship and other opportunities should reach out to the Office of Prestigious Awards atOPA@ucf.edu.

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Joshua Taggart – ucf – nasa Joshua Taggart chose 性视界传媒 for its reputation in engineering as the No. 1 supplier of talent to the nation鈥檚 aerospace and defense industries (Aviation Week Network). (Photo courtesy of Joshua Taggart)
性视界传媒鈥檚 Summer 2026 Commencement Set for July 31-Aug. 1 /news/ucfs-summer-2026-commencement-set-for-july-31-aug-1/ Fri, 24 Jul 2026 12:58:16 +0000 /news/?p=154305 Graduates will hear from听distinguished听alumni听who鈥檝e听made significant contributions听in听the Orlando community.

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性视界传媒 will award more than 4,900 degrees during this summer鈥檚 ceremonies, continuing its record-setting momentum in preparing highly skilled graduates for in-demand fields, including engineering, computer science, business, nursing, and digital and emerging media.

Worth noting among this graduating class:

  • Roughly 30% of the undergraduate students receiving their degrees are the first in their families to earn their diploma.
  • More than 25% of this term’s degrees are tied to STEM majors.
  • About 30% of the undergraduate graduating class are Pell Grant recipients.

性视界传媒 is the leading producer of talent among 性视界传媒鈥檚 universities, awarding roughly 19,000 degrees annually to Knights who go on to work in high-demand industries. About 85% of our alumni stay in 性视界传媒 because of the ample opportunity to thrive as part of our state鈥檚 workforce.

Graduates will hear from听three听esteemed speakers听鈥 all 性视界传媒 graduates 鈥斕齱hose leadership and impact听have听benefited听our region:

  • Psychology alum听Allen Johnson听鈥81,听chief听venue听officer for听City听for听Orlando Venues
  • Journalism alum Tanya (Easterling) Hill 鈥97, market president for Central 性视界传媒 for 性视界传媒 Blue
  • Criminal听justice听alum听Fred Kittinger 鈥80, 性视界传媒鈥檚 former听senior associate vice president for government and community relations
Photo collage of three portraits, from left to right, of Fred Kittinger, Tanya Hill and Allen Johnson
(Left to Right): Fred Kittinger ’80, Tanya Hill ’97 and Allen Johnson ’81 will return to their alma mater as this summer’s commencement keynote speakers.

Commencement Festivities

Held in the Addition Financial Arena, summer commencement will take place over three ceremonies spanning Friday, July 31, and Saturday, Aug. 1.

All guests, including children and infants,鈥痭eed a ticket for admission. All graduates who have filed an intent to graduate will receive five commencement ceremony tickets when they pick up their regalia packet.

Guests who do not have tickets may watch the鈥痩ive ceremony via a simulcast viewing鈥痠n the FAIRWINDS Alumni Center and the Student Union. Ceremonies will also be .

Commencement Photo-ops Across 性视界传媒

Black and white map of 性视界传媒's main campus with words overlayed that read: Picture Perfect: 性视界传媒's most iconic grad photo spots. Circle photos point to pins on the map featuring: Boardwalk, Student Union, Duke Energy Welcome Center, Reflecting Pond, Addition Financial Arena, Charging Knight Statue and inside Student Union Pegasus Seal.

Map of 性视界传媒 Downtown's Campus with words overlayed that read: Picture Perfect, 性视界传媒 Downtown's most iconic grad photos spots. Circle photos highlight pins on map featuring UnionWest, Corner of Livingston St. and N. Terry Ave., Dr. Phillips 性视界传媒 Commons, Communications and Media Building, Seneff Plaza, Luminary Green Park, Dr. Phillips Academic Commons.
性视界传媒 Downtown’s most photographic locations for grad pictures.

Graduating Knights are unable to take photos at the Acrisure Bounce House football stadium this semester due to ongoing construction.

Grad Walk

On Thursday,听July听30,听4:30-7 p.m. (doors close at 6 p.m.),听summer听graduates are invited to a photo-op 鈥 Grad Walk 鈥 within the Addition Financial Arena. This will be a first-come, first-served occasion for graduates and up to 10 of their well-wishers to take photos and videos on the ceremony stage.鈥疓raduates听are required to听register at听.

Male in traditional graduation cap and gown raises arms in celebration while pointing to diploma holder with Pegasus seal in center
All commencement ceremonies are livestreamed. (Photo by Antoine Hart)

Commencement Schedule

Graduates and guests can review the below commencement ceremony schedule, listing colleges, ceremony听dates听and streaming links:

Friday,听July听31

6听p.m.

College of Arts and Humanities

College of Community Innovation and Education

College of Graduate Studies

Rosen College of Hospitality Management

Saturday,听Aug. 1

9 a.m.

Barry S. Miller听College of Business

College of Health Professions and Sciences

College of Medicine

College of Nursing

 

2:30听p.m.

College of Engineering and Computer Science

College of Optics and Photonics

College of Sciences

 

For more details and FAQs about听Summer听2026 commencement celebrations, visitucf.edu/graduation.

Commencement Speakers

Portrait of gray-haired man with beard in blue business suit standing in front of windows
Allen Johnson ’81 graduated with a degree in psychology.

Allen Johnson 鈥81

Chief Venues Officer, City of Orlando Venues

Allen Johnson 鈥81 has served as chief venues officer of Orlando Venues since 2004, overseeing the City of Orlando’s diverse portfolio of Kia Center, Camping World Stadium, Tinker Field, Leu Gardens and the Mennello Museum of American Art.

Johnson brings decades of venue management experience from leadership roles across 性视界传媒. Under Johnson’s leadership, Orlando Venues has evolved into a premier, globally recognized destination for sports, entertainment and culture, welcoming millions of guests each year while strengthening Central 性视界传媒’s reputation as a world-class destination.

A proud 性视界传媒 graduate with a bachelor’s degree in psychology, he has earned numerous honors, including the 2025 International Association of Venue Managers Foundation Legacy Award, the SPORTYS Executive of the Year Award and the Downtowner of the Year Award.

He remains active in the International Association of Venue Managers (IAVM), serving as past chairman and trustee of the foundation board, while also contributing to organizations that include the Greater Orlando Sports Commission, 性视界传媒 Citrus Sports, Victim Service Center and the .

Portrait of smiling woman wearing bright red lipstick and brown, curly, shoulder-length hair.
Tanya Hill graduated with a degree in journalism.

Tanya (Easterling) Hill 鈥97

Market President for Central 性视界传媒, 性视界传媒 Blue

Tanya Hill 鈥97听is 性视界传媒 Blue鈥檚 market president for Central 性视界传媒,听responsible for听regional business and community engagement in a 9-county region.

Throughout her more than 25-year career, she has worked with reputable brands including Chick-fil-A, Target and Walt Disney World to drive business results through strategic partnerships.

Hill is passionate about investing time in the community and has been involved with听numerous听community and civic organizations. She currently serves on the board of directors for the听African American Chamber of Commerce of Central 性视界传媒, 4Roots Foundation, Orlando Economic听Partnership听and the Winter Park Health Foundation.

Hill holds a bachelor鈥檚 degree in journalism from 性视界传媒.

Portrait of smiling, gray-hair man in dark business suit jacket with arms crossed in front of him as his right hand holds a set of glasses
Fred Kittinger graduated with a degree in criminal justice.

Fred Kittinger 鈥80

Former Senior Associate Vice President for Government and Community Relations, 性视界传媒

A native of central 性视界传媒, Fred Kittinger 鈥80 recently retired as senior associate vice president for government and community relations at 性视界传媒, where he served for more than 22 years.

He worked alongside local and state leaders to help foster some of 性视界传媒’s most transformative achievements, including the approval of 性视界传媒鈥檚 College of Medicine, the creation of the world-class 性视界传媒 Interactive Entertainment Academy, the development of 性视界传媒 Downtown, the expansion of the 性视界传媒 Business Incubation Program and investments that enhanced the student experience and advanced regional impact.

Prior to his career at 性视界传媒, Kittinger served as chief of staff to Orlando Mayor Glenda Hood and previously as vice president of government relations for the Greater Orlando Chamber of Commerce. He began his career as a legislative aide to state Senator George Stuart of Orlando.

Reflecting his commitment to the community, Kittinger currently serves on the board of directors for Junior Achievement of Central 性视界传媒 (past chair), Central 性视界传媒 Council for Scouting America and Legacy Pointe at 性视界传媒.

Kittinger graduated from 性视界传媒鈥檚 criminal justice program and earned his master’s degree in public administration from 性视界传媒 State University.

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ucf-commencement-speakers-2026-summer (Left to Right): Fred Kittinger, Tanya Hill and Allen Johnson 2026_Grad-Map_1200x800 ucf-downtown-photos-graduation 性视界传媒 Downtown's most photographic locations for grad pictures. ucf-commencement-antoine-hart (Photo by Antoine Hart) Allen Johnson pic -ucf commencement Allen Johnson '81 graduated with a degree in psychology. Tanya Hill-性视界传媒 Commencement Tanya Hill graduated with a degree in journalism. Fred-Kittinger-性视界传媒 Commencement
New 性视界传媒 Study Links Microgravity, Space Radiation to Accelerated Aging /news/new-ucf-study-links-microgravity-space-radiation-to-accelerated-aging/ Tue, 07 Jul 2026 14:12:21 +0000 /news/?p=154085 Findings from College of Medicine Professor Michal Masternak and his team suggest spaceflight stressors may accelerate aging in the liver. This discovery could inform future medical research to understand aging on Earth and protect space travelers.

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What happens to the human body in space may help scientists create new anti-aging therapies.

性视界传媒 Professor Michal Masternak and his team have identified molecular changes in the liver that happen when space travelers experience radiation and microgravity. These changes 鈥 that resemble accelerated aging 鈥 provide new insight into how prolonged space missions may increase health risks for astronauts and reveal potential targets for therapies that could combat age-related diseases on Earth.

鈥淛ust 24 hours after radiation exposure, there are many genetic changes in the liver that are remarkably similar to what happens during aging.鈥 鈥 Professor Michal Masternak

鈥淲e focused on the liver because it is one of the major metabolic organs in our body,鈥 says Masternak, leader of the College of Medicine鈥檚 aging and space medicine research efforts. 鈥淲hat we found was that just 24 hours after radiation exposure, there are many genetic changes in the liver that are remarkably similar to what happens during aging. We can assume that if someone were in space much longer, the damage could be much greater.鈥

The findings were recently published in听GeroScience.

Portrait of bald man wearing glasses and white lab coat standing in front of blue lab bench
Professor Michal Masternak says the space industry provides unique opportunities to study aging at an accelerated pace. (Photo by Eddy Duryea 鈥13鈥)

 

Navigating the Science

For their study, 性视界传媒 researchers and scientists from the U.S. created a simulated deep space environment in the lab. The team exposed animal models to simulated microgravity for 14 days and galactic cosmic radiation and solar particle events at NASA Space Radiation Laboratory trying to mimic the dosage that astronauts would be exposed to during a trip to Mars.

The exposure triggered noticeable and potentially harmful changes in the liver, including increased cellular senescence (aging and decreased cell function), inflammation and fibrosis. Left untreated, these conditions can eventually lead to declining and even failing organ function.

The research team then compared their results with data collected from astronaut blood samples taken during the NASA Twins Study and Inspiration4 astronauts. They saw similar genetic changes in blood.

鈥淲e鈥檝e got this raw data from human studies, and they show that some of these changes are similar,鈥 Masternak says. 鈥淭hat tells us we鈥檙e identifying useful molecular targets that one day could help protect astronauts during long-duration space missions.鈥

They听also听went a step further to see听whether the听changes could be treated. They听identified听a group of molecules known as antagomirs that alter several aging and inflammatory genetic pathways听by interacting with the body鈥檚听microRNA. This system could pinpoint promising听future听therapies for space travelers.

Three men and one woman dressed in white lab coats and blue gloves on their hands stand shoulder to shoulder in lab setting
(From left to right): Biotechnology graduate student Sarah Siddiqi, researcher Mishfak Mansoor, 性视界传媒 Professor Michal Masternak and biomedical sciences doctoral student Md Tanjim Alam. (Photo by Eddy Duryea 鈥13鈥)

Understanding Aging in the Space Age

Masternak says听the nation鈥檚听growing space industry provides a unique opportunity to study aging at an accelerated pace.

鈥淰ery often when we study different aging processes, it takes time,鈥 he says. 鈥淓ven in humans, it鈥檚 almost impossible because it would take decades. But if we see some acceleration of aging in space, then we can translate it to human studies. We can observe processes happening much faster, understand them better and eventually use that knowledge to improve health for people here on Earth.鈥

鈥淚f we see some acceleration of aging in space, then … we can observe processes happening much faster, understand them better and eventually use that knowledge to improve health for people here on Earth.鈥 鈥 Masternak

Those discoveries could eventually lead to therapies that slow age-related diseases, preserve organ function and improve quality of life for everyone as they age.

鈥淥ur understanding of aging is very complex,鈥 Masternak says. 鈥淎ging isn’t simply wrinkles or cosmetic changes. It鈥檚 the gradual and cascading failure of multiple organs and biological systems that happen at the same time. By understanding what starts that process and where it happens, we have a better chance of preventing many diseases before they develop. That is one of the biggest outstanding questions.鈥

Students Positioned at the Forefront of Space Medicine

College of Medicine students are also benefitting from space medicine research. Biomedical sciences Ph.D. student Md听Tanjim Alam听鈥25MS听joined Masternak’s laboratory during his听biotechnology听master’s program after initially planning to study cancer in relation to aging biology. Then he was introduced to space medicine, including processing astronaut samples from commercial space travelers to study how extreme environments affect human biology. That research has inspired him.

鈥淚 want to keep exploring the unknown,鈥 Alam says. 鈥淚 really want to understand how space travel influences human health, particularly its effects on aging and cancer.鈥

Biotechnology听graduate听student听Sarah听S.听Siddiqi听鈥24听says the interdisciplinary nature of the research attracted her to the space medicine and aging lab.

鈥淲hen people think of aging, they think only about elderly populations,鈥 says Siddiqi, who earned her bachelor鈥檚 degree as a Burnett Honors Scholar in biomedical sciences. 鈥淏ut we study aging across different stages of life and different environments, including space. I’ll always be focused on improving quality of life. I want to better understand diseases that are increasingly prevalent and find ways to recognize them earlier, before they progress to later stages.鈥


Funding and Disclosure:

Representing听性视界传媒,听Natalie Hayslip听鈥24听served as first author, while听Sarah Ashiqueali听鈥21MS 鈥24PhD, Xiang Zhu, Ridwan Hussein听鈥22听and听Mishfak听Mansoor also contributed to the research.听Researchers from听Rensselaer Polytechnic Institute, Weill Cornell Medicine,听Universidade听Federal de Pelotas,听the听University of听Pittsburgh听and听the听University of North Carolina at Chapel听Hill听also听contributed.

This work was supported by the National Science Foundation Award Number (FAIN): 2317758(MMM), Ed and Ethel Moore Alzheimer鈥檚 Disease Research Program of the听性视界传媒 Department of Health,听Public Health Research, Biomedical Research Program听24A12 (MMM), and the National Science Centre, Poland UMO-2023/51/B/NZ5/00498 (MMM).

Any opinions, findings, and conclusions or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the views of the awarding agencies.

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Dr. Masternak and students, space aging research-medicine Professor Michal Masternak says the space industry provides unique opportunities to study aging. Michal Masternak-性视界传媒-space-aging-research From L to R: Sarah Siddiqi, Mishfak Mansoor, Dr. Michal Masternak and Md Tanjim Alam. (Photo by 性视界传媒 College of Medicine)
性视界传媒 Researcher Studying Probiotics to Fight Acid Reflux, Esophageal Cancer /news/ucf-researcher-studying-probiotics-to-fight-acid-reflux-esophageal-cancer/ Wed, 03 Jun 2026 13:00:37 +0000 /news/?p=153513 Associate Professor Claudia Andl is examining how a simple probiotic can treat the damage from acid reflux disease, a condition that affects one-fourth of Americans and increases their risk for esophageal cancer.

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Patients with acid reflux, which occurs when stomach acid pushes up into the esophagus, know the symptoms all too well: heartburn, belching, chest pain and trouble swallowing. In addition to these ailments, acid reflux also increases the risk of esophageal cancer, which has a five-year survival rate of about 22%, according to the American Cancer Society

性视界传媒 College of Medicine Associate Professor Claudia Andl, a throat and oral cancer researcher, is investigating how a simple probiotic could treat and prevent both conditions..

性视界传媒 College of Medicine Associate Professor Claudia Andl, a throat and oral cancer researcher, is investigating how a simple probiotic could treat and prevent both conditions. The research is funded by a one-year, more than $380,000 grant from the 性视界传媒 Department of Health鈥檚 性视界传媒 Cancer Innovation Fund.

Probiotics are live microorganisms 鈥 usually bacteria or yeasts 鈥 that support and strengthen health by increasing the body鈥檚 population of healthy cells. Many people take probiotics to improve gut health and digestion. Andl鈥檚 research is focused on using a healthy bacteria called Lactobacillus spp. to treat esophageal damage caused by acid reflux and improve the microbial environment in the esophagus to reduce the risk of cancer.

In patients with acid reflux 鈥 as well as gastroesophageal reflux disease (GERD), a chronic and more severe form of the digestive condition 鈥 stomach acid burns through the lining of the esophagus, causing inflammation and DNA damage to surrounding cells. Over time, those cellular changes can create a condition called Barrett鈥檚 esophagus, which increases the risk for esophageal cancer. In addition, when the throat鈥檚 bacterial environment becomes dominated by stomach acids and salts, healthy bacteria struggle to survive. Harmful bacteria take their place, causing further cell damage and inflammation that increases cancer risk. Introducing Lactobacillus spp. into disease models has solved both issues.

鈥淲e all talk about how important it is to eat yogurt or drink kombucha so that we maintain a healthy bacterial residence in all your organs. And it鈥檚 the same in the esophagus.鈥

鈥淭he reintroduction of beneficial bacteria works two-fold,鈥 Andl says. 鈥淚t restores a normal environment again, but also these Lactobacilli are known to suppress inflammation and repair the DNA damage.鈥

鈥淲e all talk about how important it is to eat yogurt or drink kombucha so that we maintain a healthy bacterial residence in all your organs,鈥 Andl continues. 鈥淎nd it鈥檚 the same in the esophagus.鈥

Early results have shown a reduction in Barrett鈥檚 esophagus, and if cancer develops at all, it occurs much later than in models not treated with the probiotic.

Andl says she hopes her research will inform new therapies and provide more information on how to keep the body鈥檚 microbial balance healthy to fight disease. She notes this is especially important as data also shows Barett鈥檚 esophagus and esophageal cancer are increasing in patients under ages 60-70, the average age for these patient populations.

鈥淲e aim to improve outcomes for the large number of reflux patients at risk for cancer,鈥 Andl says. 鈥淧laying a role in that would be incredibly rewarding.鈥

Andl joined 性视界传媒 in 2016 after receiving her Ph.D. in cell biology from the University Duisburg-Essen in Germany and conducting postdoctoral research at the University of Pennsylvania.


This research is sponsored by the 性视界传媒 Cancer Innovation Fund and the 性视界传媒 Department of Health.

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性视界传媒 Scientist Leads Research to Break Through Harmful Bacterial 鈥淔ortresses鈥 /news/ucf-scientist-leads-research-to-break-through-harmful-bacterial-fortresses/ Mon, 01 Jun 2026 13:19:55 +0000 /news/?p=153496 Continuing her work with antibiotic-resistant bacteria, Renee Fleeman is understanding how a bioengineered peptide can curb severe infections for patients.

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College of Medicine听Assistant Professor听Renee Fleeman听continues听to refine a powerful听therapy for drug-resistant bacteria that pierces the gooey coating that anchors and protects such germs from the drugs we take to kill them.

Her听research, backed by a five-year $813,130 National Institute of Allergy and Infectious Diseases grant, found that an antimicrobial peptide naturally found in cows weakens the biofilm defenses of Klebsiella pneumoniae bacteria and destroys it.

Now in their fourth year of research, Fleeman and her lab have discovered exactly how the peptide works in findings published in PLOS Pathogens.

鈥淥ur research is very advantageous for healthcare because about 80% of bacterial infections being treated in the clinic are bacteria living in a biofilm state, which makes them resistant to virtually every antibiotic available,鈥 she says.

The results听represent听a critical step to potentially applying this peptide as a therapy and eventually treating patients,听as the findings听show they can and kill biofilm-embedded bacteria in animal models.

Man wearing black glasses and white lab coat holds up dish with jelly circles between his blue gloved hands
Robert Beckman 鈥23 shows an isolated experiment that demonstrates how their peptide kills K. pneumoniae, which is a critical step before testing in animal or human models.

Parsing out the Peptide

K. pneumoniae is found in the intestines and is usually harmless, however, the bacterium develops resistance over a person鈥檚 lifetime as they are exposed to antibiotics. The bacteria also can spread from the intestine to other parts of the body in immunocompromised patients and those who have internal ruptures or exposure to contaminated medical devices. That exposure can lead to pneumonia, urinary tract or wound infections.

鈥淲hat happens is the bacteria听infects听the wound, proliferates, and then invades through the bloodstream听where it travels听to the liver, kidneys and spleen,鈥 Fleeman听says. 鈥淲e听found听our peptide听was able to decrease the bacteria听at the source while limiting听the bacteria鈥檚听ability to move听through the blood.鈥

Fleeman and her lab鈥檚 most recent study found that the peptide triggers a dual stress response that tricks the bacteria to break out of their protective biofilm.

They discovered the genetics of a specific protein in the bacterium when turned on in the germ causes it to break from its own protective biofilm. The peptide, in effect, damages the protection and then stresses the bacterium into shedding its protection, making the germ more sensitive to antibiotics and the body鈥檚 immune system.

鈥淏y听hitting the membrane as well as protein synthesis at the same time, it’s听a double punch that triggers a genetic听change听in the cell to make it think it needs to break out of听the biofilm as a response to our peptide,鈥 Fleeman听says.

The team says their sustained research aims to demonstrate that their peptide can work synergistically with existing antibiotics. They envision long-term applications could involve a topical cream that weakens the bacteria鈥檚 defenses and allows standard antibiotics to work more effectively.

鈥淲e鈥檙e moving our research听forward听and we鈥檙e very hopeful,鈥 Fleeman听says.

Dr. Renee Fleeman stands with mixed group of six men and women, all in white lab coats, with shelves of lab equipment around them.
Renee Fleeman鈥檚 lab group is comprised of students who, under Fleeman鈥檚 mentorship, gain valuable research experience. (Photo by Kadeem Stewart)

Preparing for the Post-Antibiotic Era

The first author of this new work听is听Robert Beckman听鈥23, who graduated听from 性视界传媒听with a听bachelor鈥檚 degree in health sciences,听managed听Fleeman鈥檚 lab听and is now on his way to听the University of Michigan听for his Ph.D.

His听previous听work as an EMT gave him firsthand exposure to听infectious diseases and their impact on听patients.听He听says听helping to lead the study and听working with听Fleeman helped prepare him for a career in medical research.

鈥淚 have developed a strong foundation in research and gained insight into the many components that define an effective scientist,鈥 he听says. 鈥淢y long-term goal is to remain in academia and eventually lead my own research lab.听I plan to continue focusing on bacteriology, with a particular emphasis on pathogenic bacteria and drug discovery applications.鈥

Funding and Disclosure:

Research reported in this publication was supported by the National Institute听of Allergy听and Infectious Diseases of the National Institutes of Health under Award Number R00AI163295. The content is solely the responsibility of the authors and does not necessarily听represent听the official views of the National Institutes of Health.

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Robert Backman lab (14) Robert Beckman 鈥13 shows an isolated experiment that demonstrates how their peptide kills K. pneumoniae, which is a critical step before testing in animal or human models. Fleeman and lab students Renee Fleeman鈥檚 lab group is comprised of students who, under Fleeman鈥檚 mentorship, gain valuable research experience. (Photo by Kadeem Stewart)
性视界传媒 Researcher Develops 鈥淪mart, Tiny Bubbles鈥 to Treat Cancer and Heart Disease /news/ucf-researcher-develops-smart-tiny-bubbles-to-treat-cancer-and-heart-disease/ Wed, 20 May 2026 14:21:52 +0000 /news/?p=153299 Dinender Singla developed innovative technology and has formed a company to get the treatment ready for clinical trials.

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A cell 500 times thinner than a human hair could heal hearts and kill cancer cells, thanks to a patent-pending technology created by a 性视界传媒 researcher and now licensed to a university donor in hopes of getting it to clinical trials.

Dinender Singla, professor and head of the College of Medicine鈥檚 Division of Metabolic and Cardiovascular Sciences, developed a system that turns exosomes 鈥 vesicles that cells secrete to communicate with one another 鈥 into delivery vehicles for medical treatments.

This innovative technology, for which 性视界传媒 is seeking patent protection, places therapeutics inside exosomes and coats them with cell-specific markers that direct them to an exact area of the body to deliver the drug.

鈥淚 call these smart tiny bubbles,鈥 Singla says. 鈥淢illions of people have heart disease, and they take multiple drugs in extremely high doses. But we have no way to be certain these drugs are getting to where they need to go. We need innovative technologies to get treatments exactly where they need to go to cure the problem.鈥

Two men and a woman in white lab coats stand to right of computer monitor, which is flanked on the opposite side by two men in business coats.
From left to right: Research Scientist Chandrakala Aluganti Narasimhulu, Jonatas De Mendonca Rolando ’23MS ’26PhD,听 a 性视界传媒 post-doc, 性视界传媒 doctoral student Omonzejie Imaralu 鈥22MS, Dinender Singla and Chakri Toleti.

How the Therapy Works

This discovery is part of Singla鈥檚 work to provide therapies to treat and prevent heart disease, including heart damage caused by cancer treatments such as chemotherapy and targeted radiation to the chest. That heart damage seems to be caused by inflammatory factors that treatments use to kill cancer cells. Technology developed by Singla encapsulates anti-inflammatory heart treatments in exosomes and then delivers the drug to the exact area of heart damage.

鈥淭hey can treat cancer and protect the heart.鈥 鈥 性视界传媒 Professor Dinender Singla

As part of this research, Singla鈥檚 team also developed technologies to deliver cancer-killing drugs inside exosomes. They chose triple-negative breast cancer for their research, the deadliest form of the disease, with a 77%鈥78% five-year survival rate. In the lab, the therapy showed significant promise in killing cancer cells 鈥 at much lower doses that are used in chemotherapy 鈥 while also protecting the heart. So the exosome therapy could help cancer patients without the severe side effects of chemotherapy.

鈥淭hese therapies can work hand-in-hand,鈥 Singla said. 鈥淭hey can treat cancer and protect the heart.鈥

Financial Investment is Key for Drug Development

The next step will be manufacturing the therapy for clinical use and advancing into FDA clinical trials for heart disease and cancer treatment. To help accelerate that path, Singla partnered with Orlando investor and 性视界传媒 donor Chakri Toleti, a healthcare technology entrepreneur focused on building category-defining businesses through AI and agentic platforms, biomedical innovation and ambient intelligence including most recently care.ai, which was acquired by Stryker in 2024.

Through his innovation fund, TCapital, Toleti backs transformative technologies designed to improve healthcare delivery and reduce human suffering at scale. Together, Singla and Toleti invested in and formed Exomic to fund continued research, clinical development, and commercialization of the technology.

鈥淭his was an opportunity to do something truly innovative in cancer and cardiovascular treatment.鈥 鈥 Chakri Toleti, 性视界传媒 donor

Toleti says his passion for advancing cancer research is deeply personal after losing his father to the disease.

鈥淭his was an opportunity to do something truly innovative in cancer and cardiovascular treatment,鈥 he says. 鈥淒r. Singla鈥檚 work represents a fundamental shift toward new biomedical platforms not only in how targeted therapies are delivered in the human body, but in how we think about treatment and healing itself.鈥

Such public-private partnerships are one of the goals of , which drives innovation, enterprise, and collaboration across disciplines.

鈥淒r. Singla鈥檚 groundbreaking exosome delivery system perfectly exemplifies how university innovation translates into significant, life-saving benefits for society,鈥 says Winston V. Schoenfeld, vice president for research and innovation. 鈥淎s demonstrated by the creation of Exomic, industry partnership is essential for driving such pioneering technologies towards successful translation and real-world clinical use.鈥

The effort is also providing exciting learning opportunities for College of Medicine graduate students. Jonatas De Mendonca Rolando 鈥23MS 鈥26PhD听earned his Ph.D. in biomedical sciences earlier this month. He is staying at 性视界传媒 as a post-doctoral researcher to continue creating the exosome therapy.

He helped develop protocols and procedures for the delicate technology and saw its impact in the lab. He鈥檚 excited to have a financial supporter who can help take the therapy from lab to, he hopes, patients.

鈥淚t鈥檚 been amazing to part of a high-tech project and see leadership in science,鈥 he says. 鈥淚 am very excited for my future.鈥

Researcher Background

Singla is the AdventHealth Endowed Chair of Cardiovascular Sciences at the Burnett School of Biomedical Sciences and is a faculty fellow with the 性视界传媒 Office of Research. He earned his bachelor鈥檚 and master鈥檚 degrees from Punjabi University, Patiala, India, and his Ph.D. from the Post Graduate Institute of Medical Education and Research, Chandigarh, India. He has published more than 100 peer-reviewed papers and has continually been funded by the American Heart Association and/or the National Institutes of Health since 2004.

About TCapital

TCapital is an AI, Frontier Tech and Life Sciences innovation fund investing in category-defining platforms and infrastructure. Founded by healthcare technology entrepreneur Chakri Toleti, T-Capital invests in companies shaping the future of treatment, care, and biomedical innovation. For more information, visit TCapital.com.

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Dr. Singla and team From left to right: Research Scientist Chanderkala Aluganthi, Jonatas Rolando, now a 性视界传媒 post-doc, 性视界传媒 graduate student Omonzejie Imaralu 鈥22MS, Singla and Chakri Toleti